Reparagen consists of two patented, all natural extracts: Vincaria® and RNI 249® In the Vincaria Unum In Dei (once-a-day) Efficacy (VUIDE) trial, over 90% of the patients taking a single 100mg daily dose of Vincaria experienced significant improvement in joint health and function in less than 5 days (as compared to placebo).3 Reparagen contains 3 times the effective dose.
In a study with Case Western Reserve University using human cartilage explants, the extract RNI 249 was shown to increase the cells production of IGF-1, a natural growth factor responsible for rebuilding and repairing cartilage.7,8 Reparagen contains 1500 milligrams of RNI 249.
In the subsequent, product specific, peer-reviewed, published positive-controlled clinical trial, 93% of participants taking Reparagen experienced significant improvement in overall joint health, as measured by their physicians, and many within seven days.9
In this clinical trial, the positive control was Glucosamine sulfate. As measured by both the patients and physicians, Reparagen worked significantly better that Glucosamine sulfate. Reparagen is the only natural supplement for joint health and mobility with research supported in part from the US National Institutes of Health: The National Institute of Aging.10
Clinically Better than Glucosamine Sulfate
Reparagen is the reliable solution for joint health. It works at a genetic level to not only help support a healthy inflammatory response,2,4 but in human cells, it has been shown to increase cartilage growth and repair.7,8 Importantly, in a published, peer-reviewed clinical study, over 93% of the patients taking Reparagen had significant improvement in both joint mobility and flexibility, many in less than seven days.9
Reparagen was reviewed by the National Advertising Division (NAD) of the Council of Better Business Bureaus, which monitors “truth in advertising.” NAD found that there was substantial evidence to support that Reparagen was “…a revolutionary solution, a breakthrough, all-natural treatment in joint pain that does what no other products have done before,” that it “…actually helps alleviate Arthritis symptoms and increases flexibility and mobility” and that it may help “…in as fast as 7 days.”
Reparagen is the only natural supplement for joint health and mobility with research supported in part from two US National Institutes of Health: The National Institute of Arthritis and Musculoskeletal Disease and The National Institute of Aging (1R43AG024733-01).
2 Aliment Pharmacol Ther 1998; 12: 1279±1289.
3 Inflammation Res, 2001, 50:442–448
4 Free Rad Bio Medicine, 2000, 29(1):71–78
5 N Eng J Med, 2006, 354:795-808
6 2007 Gallup Study of Joint Health and Glucosamine
7 Inflammation Research 54: Supplement 2, pp 115, 2005
8 BMC Complementary and Alternative Medicine 2006, 6:13
9 BMC Complementary and Alternative Medicine 2007, 7:34
10 US NIH Grant No 1R43AG024733-01
11 Journal of Translational Medicine 2008, 6:3